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Literature summary for 2.7.7.19 extracted from

  • Rouhana, L.; Wang, L.; Buter, N.; Kwak, J.E.; Schiltz, C.A.; Gonzalez, T.; Kelley, A.E.; Landry, C.F.; Wickens, M.
    Vertebrate GLD2 poly(A) polymerases in the germline and the brain (2005), RNA, 11, 1117-1130.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.19

Activating Compound

Activating Compound Comment Organism Structure
additional information the enzyme is kept inactive in the G complex prior to the onset of meiotic maturation. Activation could involve the removal of inhibitory modifications of GLD2 Xenopus laevis

Cloned(Commentary)

Cloned (Comment) Organism
expression in Xenopus oocyte Mus musculus
expression in Xenopus oocyte Homo sapiens
expression in Xenopus oocyte Xenopus laevis

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Xenopus laevis 5737
-
nucleus
-
 Xenopus laevis 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 PAP activity is attributed to the protein GLD2
-
Mus musculus
-
 PAP activity is attributed to the protein GLD2
-
Xenopus laevis
-
 PAP activity is attributed to the proteins XIGLD-2A and XIGLD-2B
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
brain
-
 Homo sapiens
-
oocyte
-
 Xenopus laevis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNAn
-
 Mus musculus diphosphate + RNAn+1
-
 ?
ATP + RNAn
-
 Homo sapiens diphosphate + RNAn+1
-
 ?
ATP + RNAn
-
 Xenopus laevis diphosphate + RNAn+1
-
 ?

Synonyms

Synonyms Comment Organism
poly(A) polymerase
-
 Mus musculus
poly(A) polymerase
-
 Homo sapiens
poly(A) polymerase
-
 Xenopus laevis

Cofactor

Cofactor Comment Organism Structure
additional information interaction with cytoplasmic polyadenylation factors, including CPSF and CPEB, and with target mRNAs Xenopus laevis
additional information interaction with Xenopus CPEB in vitro Mus musculus
additional information interaction with Xenopus CPEB in vitro Homo sapiens