Literature summary for 2.7.7.15 extracted from

Friesen, J.A.; Liu, M.F.; Kent, C.
Cloning and characterization of a lipid-activated CTP:phosphocholine cytidylyltransferase from Caenorhabditis elegans: identification of a 21-residue segment critical for lipid activation (2001), Biochim. Biophys. Acta, 1533, 86-98.

Search for more literature for 2.7.7.15

Cloned(Commentary)

Cloned (Comment)	Organism
wild-type and truncated forms	Caenorhabditis elegans

Protein Variants

Protein Variants	Comment	Organism
additional information	mutants truncated after amino acids 225 or 245 are active in the absence of lipids and not further activated in the presence of lipids, mutants truncated after amino acids 226, 281 or 319 are activated by lipid similar to wild-type enzyme	Caenorhabditis elegans

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
additional information	-	additional information	-	Caenorhabditis elegans

Organism

Organism	UniProt	Comment	Textmining
Caenorhabditis elegans	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
wild-type and truncated forms	Caenorhabditis elegans

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
11	-	-	Caenorhabditis elegans

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CTP + choline phosphate	-	Caenorhabditis elegans	diphosphate + CDPcholine	-	?

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
additional information	-	additional information	-	Caenorhabditis elegans

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Release 2023.1 (January 2023)