Activating Compound | Comment | Organism | Structure |
---|---|---|---|
AMP-activated kinase | - |
Homo sapiens | |
AMP-activated kinase | - |
Rattus norvegicus | |
AMP-activated kinase | - |
Mus musculus | |
additional information | does not require the presence of exogenous lipids for optimal activity | Homo sapiens | |
additional information | does not require the presence of exogenous lipids for optimal activity | Rattus norvegicus | |
additional information | does not require the presence of exogenous lipids for optimal activity | Mus musculus | |
paramethoxyamphetamine | stimulates activity | Homo sapiens | |
paramethoxyamphetamine | stimulates activity | Rattus norvegicus | |
paramethoxyamphetamine | stimulates activity | Mus musculus |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
- |
Rattus norvegicus |
- |
Saccharomyces cerevisiae |
- |
Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aminoimidazole-4-carboxamide | downregulates Pcyt2 activity | Homo sapiens | |
aminoimidazole-4-carboxamide | downregulates Pcyt2 activity | Mus musculus | |
aminoimidazole-4-carboxamide | downregulates Pcyt2 activity | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.053 | - |
Ethanolamine phosphate | - |
Rattus norvegicus | |
0.065 | - |
CTP | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
cytosol | - |
Rattus norvegicus | 5829 | - |
cytosol | - |
Mus musculus | 5829 | - |
membrane | associated with the membranes of the rough endoplasmic reticulum | Homo sapiens | 16020 | - |
membrane | associated with the membranes of the rough endoplasmic reticulum | Rattus norvegicus | 16020 | - |
membrane | associated with the membranes of the rough endoplasmic reticulum | Mus musculus | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
SDS-PAGE | Homo sapiens |
50000 | - |
SDS-PAGE | Rattus norvegicus |
50000 | - |
SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | Q922E4 | - |
- |
Rattus norvegicus | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
- |
Rattus norvegicus |
- |
Saccharomyces cerevisiae |
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipocyte | - |
Homo sapiens | - |
adipocyte | - |
Mus musculus | - |
adipocyte | high Pcyt2 mRNA content. Negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA | Mus musculus | - |
brain | low Pcyt2 mRNA content | Mus musculus | - |
heart | - |
Homo sapiens | - |
heart | - |
Mus musculus | - |
heart | very low level of Pcyt2alpha | Homo sapiens | - |
kidney | - |
Homo sapiens | - |
kidney | - |
Mus musculus | - |
kidney | negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA | Mus musculus | - |
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Mus musculus | - |
liver | low Pcyt2 mRNA content. Negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA | Mus musculus | - |
liver | Pcyt2 stays constant throughout the rat adult stage | Rattus norvegicus | - |
additional information | Pcyt2 mRNA is barely detected in human kidney | Homo sapiens | - |
skeletal muscle | low Pcyt2 mRNA content | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + ethanolamine phosphate | - |
Homo sapiens | diphosphate + CDP-ethanolamine | - |
? | |
CTP + ethanolamine phosphate | - |
Rattus norvegicus | diphosphate + CDP-ethanolamine | - |
? | |
CTP + ethanolamine phosphate | - |
Saccharomyces cerevisiae | diphosphate + CDP-ethanolamine | - |
? | |
CTP + ethanolamine phosphate | - |
Mus musculus | diphosphate + CDP-ethanolamine | - |
? | |
additional information | uses N-methylated derivatives of ethanolamine phosphate less efficiently and does not react with phosphocholine | Homo sapiens | ? | - |
? | |
additional information | uses N-methylated derivatives of ethanolamine phosphate less efficiently and does not react with phosphocholine | Rattus norvegicus | ? | - |
? | |
additional information | uses N-methylated derivatives of ethanolamine phosphate less efficiently and does not react with phosphocholine | Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Homo sapiens |
dimer | - |
Rattus norvegicus |
dimer | - |
Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
CTP:phosphoethanolamine cytidylyltransferase | - |
Homo sapiens |
CTP:phosphoethanolamine cytidylyltransferase | - |
Rattus norvegicus |
CTP:phosphoethanolamine cytidylyltransferase | - |
Saccharomyces cerevisiae |
CTP:phosphoethanolamine cytidylyltransferase | - |
Mus musculus |
Pcyt2 | - |
Homo sapiens |
Pcyt2 | - |
Rattus norvegicus |
Pcyt2 | - |
Saccharomyces cerevisiae |
Pcyt2 | - |
Mus musculus |
Pcyt2alpha | longer variant of Pcyt2 | Homo sapiens |
Pcyt2alpha | longer variant of Pcyt2 | Mus musculus |
Pcyt2beta | shorter variant of Pcyt2 | Homo sapiens |
Pcyt2beta | shorter variant of Pcyt2 | Mus musculus |