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Literature summary for 2.7.7.12 extracted from

  • Leslie, N.D.; Bai, S.
    Functional analysis of the mouse galactose-1-phosphate uridyl transferase (GALT)promoter (2001), Mol. Genet. Metab., 72, 31-38.
    View publication on PubMed
Search for more literature for 2.7.7.12

Cloned(Commentary)

Cloned (Comment) Organism
transient expression of reporter plasmids in HepG2 cells and NS20Y mouse neuroblastoma cells carrying varying fragments of the gene sequence, functional promotor search and analysis, DNA sequencing Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information construction of transgenic mice expressing a luciferase transgene under control of a 1.9 kb fragment of the UDP-glucose-hexose-1-phosphate uridylyltransferase promotor region , activity is found in most tissues with higher than expected reporter levels in neonatal brain Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-glucose + alpha-D-galactose 1-phosphate Mus musculus transcriptional regulation is complex and not directly induced by substrate levels alpha-D-glucose 1-phosphate + UDP-galactose
-
 r

Organism

Organism UniProt Comment Textmining
Mus musculus Q03249 galT gene
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-glucose + alpha-D-galactose 1-phosphate
-
 Mus musculus alpha-D-glucose 1-phosphate + UDP-galactose
-
 r
UDP-glucose + alpha-D-galactose 1-phosphate transcriptional regulation is complex and not directly induced by substrate levels Mus musculus alpha-D-glucose 1-phosphate + UDP-galactose
-
 r

Synonyms

Synonyms Comment Organism
GALT
-
 Mus musculus