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Literature summary for 2.7.6.5 extracted from
- Dependence of rela-mediated (p)ppGpp formation on tRNA identity (2011), Biochemistry, 50, 3075-3083.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | ribosome complexes formed with tight binding tRNAVal stimulate enzyme activity at lower concentrations than that required for ribosome complexes formed with the weaker binding tRNAPhe | Escherichia coli |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21 cells | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| HiTrap column chromatography | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + GTP | RelA-mediated guanosine 3'-diphosphate 5'-triphosphate synthesis requires the presence of an uncharged tRNAVal in the A-Site of a mRNA programmed ribosome | Escherichia coli | AMP + guanosine 3'-diphosphate 5'-triphosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| (p)ppGpp synthetase | - |
Escherichia coli |
| RelA | - |
Escherichia coli |
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