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Literature summary for 2.7.6.2 extracted from
- Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans (2004), Genetics, 168, 845-854.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + thiamine | Caenorhabditis elegans | the tpk-1 gene functions cell nonautonomously, as the expression of wild-type tpk-1 in one tissue can residue the function of other tissues that express only mutant tpk-1. Thiamine diphosphate can be transported across the cell membrane | AMP + thiamine diphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | P30636 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + thiamine | the tpk-1 gene functions cell nonautonomously, as the expression of wild-type tpk-1 in one tissue can residue the function of other tissues that express only mutant tpk-1. Thiamine diphosphate can be transported across the cell membrane | Caenorhabditis elegans | AMP + thiamine diphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thiamine pyrophosphokinase | encoded by tpk-1 | Caenorhabditis elegans |
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