Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | 0.5 mM, 33% inhibition | Homo sapiens | |
dADP | 0.5 mM, 34% inhibition | Homo sapiens | |
dGDP | 0.5 mM, 23% inhibition | Homo sapiens | |
dTDP | 0.5 mM, 91% inhibition | Homo sapiens | |
dUDP | 0.5 mM, 42% inhibition | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0049 | - |
dTMP | pH 7.4, 37°C | Homo sapiens | |
0.62 | - |
ATP | pH 7.4, 37°C | Homo sapiens | |
0.62 | - |
ATP | ATP in form of MgATP2- | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
24000 | - |
2 * 24000, SDS-PAGE | Homo sapiens |
50000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | term placenta | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.833 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + dTMP | - |
Homo sapiens | ADP + dTDP | - |
? | |
CTP + dTMP | 56% of the activity with ATP | Homo sapiens | CDP + dTDP | - |
? | |
dATP + dTMP | 99% of the activity with ATP | Homo sapiens | dADP + dTDP | - |
? | |
dCTP + dTMP | 45% of the activity with ATP | Homo sapiens | dCDP + dTDP | - |
? | |
dGTP + dTMP | 59% of the activity with ATP | Homo sapiens | dGDP + dTDP | - |
? | |
GTP + dTMP | 60% of the activity with ATP | Homo sapiens | GDP + dTDP | - |
? | |
UTP + dTMP | 60% of the activity with ATP | Homo sapiens | UDP + dTDP | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 24000, SDS-PAGE | Homo sapiens |