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Literature summary for 2.7.4.8 extracted from

  • Zhu, J.; Shang, Y.; Xia, C.; Wang, W.; Wen, W.; Zhang, M.
    Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules (2011), EMBO J., 30, 4986-4997.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.4.8

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Homo sapiens
expressed in Escherichia coli BL21(DE3) cells Rattus norvegicus

Crystallization (Commentary)

Crystallization (Comment) Organism
SAP97 SH3-guanylate kinase/p-LGN18 complex, hanging drop vapor diffusion method, using 0.2M ammonium nitrate, 20% (w/v) polyethylene glycol 3350 Homo sapiens
SAP97 SH3-guanylate kinase/p-LGN18 complex, hanging drop vapor diffusion method, using 0.2M ammonium nitrate, 20% (w/v) polyethylene glycol 3350 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-
membrane
-
 Rattus norvegicus 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus Q62696
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni2+-NTA agarose affinity column chromatography Rattus norvegicus
Ni2+-NTA agarose affinity column chromatography and gel filtration Homo sapiens

Synonyms

Synonyms Comment Organism
DLG1/SAP97
-
 Homo sapiens
DLG1/SAP97
-
 Rattus norvegicus
MAGUK
-
 Homo sapiens
MAGUK
-
 Rattus norvegicus
membrane-associated guanylate kinase
-
 Homo sapiens
membrane-associated guanylate kinase
-
 Rattus norvegicus

General Information

General Information Comment Organism
physiological function the guanylate kinase domain of DLG1/SAP97 binds to asymmetric cell division regulatory protein LGN in a phosphorylation-dependent manner Homo sapiens
physiological function the guanylate kinase domain of DLG1/SAP97 binds to asymmetric cell division regulatory protein LGN in a phosphorylation-dependent manner Rattus norvegicus