Application | Comment | Organism |
---|---|---|
drug development | the guanylate-kinase-deficient Escherichia coli strain relies on the presence of a plasmid-borne, functional guanylate kinase for viability. Such a strain will be beneficial to assess the role of specific amino acids of guanylate kinase in structure, function, drug activation, and drug resistance | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + GMP | Escherichia coli | signal transduction | ADP + GDP | - |
? | |
ATP + GMP | Escherichia coli TS202A | signal transduction | ADP + GDP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
guanylate-kinase-deficient | - |
Escherichia coli TS202A | - |
guanylate-kinase-deficient | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + GMP | signal transduction | Escherichia coli | ADP + GDP | - |
? | |
ATP + GMP | signal transduction | Escherichia coli TS202A | ADP + GDP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GMK | - |
Escherichia coli |
guanylate kinase | - |
Escherichia coli |