BRENDA - Enzyme Database show
show all sequences of 2.7.4.8

Guanylate kinases from human erythrocytes, hog brain, and rat liver

Agarwal, K.C.; Miech, R.P.; Parks, R.E.; Methods Enzymol. 51, 483-490 (1978)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
5,5'-dithiobis(2-nitrobenzoate)
-
Homo sapiens
5,5'-dithiobis(2-nitrobenzoate)
-
Rattus norvegicus
additional information
no inhibition by 2-mercaptoethanol, 1,4-dithiothreitol; no inhibition by guanosine, AMP, CMP, UMP, XMP, 6-thioinosine 5'-phosphate
Homo sapiens
additional information
no inhibition by 2-mercaptoethanol, 1,4-dithiothreitol; no inhibition by guanosine, AMP, CMP, UMP, XMP, 6-thioinosine 5'-phosphate
Rattus norvegicus
additional information
no inhibition by 2-mercaptoethanol, 1,4-dithiothreitol; no inhibition by guanosine, AMP, CMP, UMP, XMP, 6-thioinosine 5'-phosphate
Sus scrofa
N-ethylmaleimide
-
Homo sapiens
N-ethylmaleimide
-
Rattus norvegicus
p-chloromercuribenzoic acid
1,4-dithiothreitol reverses
Homo sapiens
p-chloromercuribenzoic acid
1,4-dithiothreitol reverses
Rattus norvegicus
p-chloromercuribenzoic acid
1,4-dithiothreitol reverses
Sus scrofa
p-hydroxymercuribenzoate
-
Homo sapiens
p-hydroxymercuribenzoate
-
Rattus norvegicus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.006
-
GMP
pH 7.5, 30C
Sus scrofa
0.01
-
dGMP
pH 7.5, 30C
Rattus norvegicus
0.01
-
dGMP
pH 7.5, 30C
Sus scrofa
0.01
-
GMP
pH 7.5, 30C
Rattus norvegicus
0.013
-
8-azaguanosine 5'-monophosphate
pH 7.5, 30C
Sus scrofa
0.018
-
GMP
pH 7.5, 30C
Homo sapiens
0.028
-
dGMP
pH 7.5, 30C
Rattus norvegicus
0.07
-
8-azaguanosine 5'-monophosphate
pH 7.5, 30C
Rattus norvegicus
0.074
-
dGMP
pH 7.5, 30C
Homo sapiens
0.091
-
8-azaguanosine 5'-monophosphate
pH 7.5, 30C
Homo sapiens
0.12
-
ATP
pH 7.5, 30C
Sus scrofa
0.18
-
ATP
pH 7.5, 30C
Rattus norvegicus
0.19
-
ATP
pH 7.5, 30C
Homo sapiens
2.1
-
6-thioguanosine 5'-monophosphate
pH 7.5, 30C
Homo sapiens
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Ca2+
no activator
Homo sapiens
Ca2+
no activator
Rattus norvegicus
Ca2+
no activator
Sus scrofa
K+
activation
Homo sapiens
K+
activation
Rattus norvegicus
K+
activation
Sus scrofa
Li+
partial activity
Sus scrofa
Mg2+
-
Rattus norvegicus
Mg2+
-
Sus scrofa
Mg2+
-
Homo sapiens
Mn2+
requirement
Homo sapiens
Mn2+
requirement
Rattus norvegicus
Mn2+
requirement
Sus scrofa
additional information
-
Homo sapiens
additional information
-
Rattus norvegicus
additional information
no activation by Sr2+ or Cs2+
Sus scrofa
Na+
activation
Sus scrofa
NH4+
activation
Homo sapiens
NH4+
activation
Rattus norvegicus
NH4+
activation
Sus scrofa
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-
Purification (Commentary)
Commentary
Organism
method that includes DEAE-cellulose and Sephadex-75 chromatography
Rattus norvegicus
method that includes DEAE-cellulose and Sephadex-75 chromatography
Sus scrofa
method that includes DEAE-cellulose, Sephadex-75 chromatography and isoelectric focusing
Homo sapiens
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Sus scrofa
-
brain
-
Rattus norvegicus
-
erythrocyte
-
Homo sapiens
-
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
28
-
-
Sus scrofa
Storage Stability
Storage Stability
Organism
0C, below, in 70% saturated ammonium sulfate, several years
Homo sapiens
0C, below, in 70% saturated ammonium sulfate, several years
Rattus norvegicus
0C, below, in 70% saturated ammonium sulfate, several years
Sus scrofa
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + 6-thioguanosine 5'-monophosphate
-
642688
Homo sapiens
ADP + 8-thioguanosine 5'-diphosphate
-
-
-
?
ATP + 6-thioguanosine 5'-monophosphate
-
642688
Rattus norvegicus
ADP + 8-thioguanosine 5'-diphosphate
-
-
-
?
ATP + 6-thioguanosine 5'-monophosphate
-
642688
Sus scrofa
ADP + 8-thioguanosine 5'-diphosphate
-
-
-
?
ATP + 8-azaguanosine 5'-monophosphate
-
642688
Homo sapiens
ADP + 8-azaguanosine 5'-diphosphate
-
-
-
?
ATP + 8-azaguanosine 5'-monophosphate
-
642688
Rattus norvegicus
ADP + 8-azaguanosine 5'-diphosphate
-
-
-
?
ATP + 8-azaguanosine 5'-monophosphate
-
642688
Sus scrofa
ADP + 8-azaguanosine 5'-diphosphate
-
-
-
?
ATP + dGMP
-
642688
Homo sapiens
ADP + dGDP
-
-
-
r
ATP + dGMP
-
642688
Rattus norvegicus
ADP + dGDP
-
-
-
r
ATP + dGMP
-
642688
Sus scrofa
ADP + dGDP
-
-
-
r
ATP + GMP
specificity
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
specificity
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
specificity
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
nucleoside monophosphate binding site is highly specific for guanine moiety
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
nucleoside monophosphate binding site is highly specific for guanine moiety
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
nucleoside monophosphate binding site is highly specific for guanine moiety
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
deoxyguanosine, guanosine are no acceptor substrates
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
deoxyguanosine, guanosine are no acceptor substrates
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
deoxyguanosine, guanosine are no acceptor substrates
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
6-thio-IMP is no acceptor substrate
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
6-thio-IMP is no acceptor substrate
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
6-thio-IMP is no acceptor substrate
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
XMP is no acceptor substrate
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
XMP is no acceptor substrate
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
XMP is no acceptor substrate
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
AMP is no acceptor substrate
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
AMP is no acceptor substrate
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
AMP is no acceptor substrate
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
CMP, UMP are no acceptor substrates
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
CMP, UMP are no acceptor substrates
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
CMP, UMP are no acceptor substrates
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + IMP
very poor substrate
642688
Homo sapiens
ADP + IDP
-
-
-
?
dATP + dGMP
-
642688
Homo sapiens
dADP + dGDP
-
-
-
?
dATP + dGMP
-
642688
Rattus norvegicus
dADP + dGDP
-
-
-
?
dATP + dGMP
-
642688
Sus scrofa
dADP + dGDP
-
-
-
?
dATP + GMP
-
642688
Homo sapiens
dADP + GDP
-
-
-
?
dATP + GMP
-
642688
Rattus norvegicus
dADP + GDP
-
-
-
?
dATP + GMP
-
642688
Sus scrofa
dADP + GDP
-
-
-
?
Temperature Optimum [C]
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
30
-
assay at
Homo sapiens
30
-
assay at
Rattus norvegicus
30
-
assay at
Sus scrofa
Temperature Stability [C]
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
30
-
at least 15 min stable from pH 5.5-8.5
Sus scrofa
50
-
10 min, inactivation
Homo sapiens
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
5.5
8.5
at least 15 min stable at 30C
Sus scrofa
pI Value
Organism
Commentary
pI Value Maximum
pI Value
Rattus norvegicus
3 isoelectric variants, predominant form: pI 4.9, agarose gel electrophoresis and isoelectric focusing
4.8
4.7
Homo sapiens
4 isoelectric variants, agarose gel electrophoresis and isoelectric focusing
-
4.9
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
5,5'-dithiobis(2-nitrobenzoate)
-
Homo sapiens
5,5'-dithiobis(2-nitrobenzoate)
-
Rattus norvegicus
additional information
no inhibition by 2-mercaptoethanol, 1,4-dithiothreitol; no inhibition by guanosine, AMP, CMP, UMP, XMP, 6-thioinosine 5'-phosphate
Homo sapiens
additional information
no inhibition by 2-mercaptoethanol, 1,4-dithiothreitol; no inhibition by guanosine, AMP, CMP, UMP, XMP, 6-thioinosine 5'-phosphate
Rattus norvegicus
additional information
no inhibition by 2-mercaptoethanol, 1,4-dithiothreitol; no inhibition by guanosine, AMP, CMP, UMP, XMP, 6-thioinosine 5'-phosphate
Sus scrofa
N-ethylmaleimide
-
Homo sapiens
N-ethylmaleimide
-
Rattus norvegicus
p-chloromercuribenzoic acid
1,4-dithiothreitol reverses
Homo sapiens
p-chloromercuribenzoic acid
1,4-dithiothreitol reverses
Rattus norvegicus
p-chloromercuribenzoic acid
1,4-dithiothreitol reverses
Sus scrofa
p-hydroxymercuribenzoate
-
Homo sapiens
p-hydroxymercuribenzoate
-
Rattus norvegicus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.006
-
GMP
pH 7.5, 30C
Sus scrofa
0.01
-
dGMP
pH 7.5, 30C
Rattus norvegicus
0.01
-
dGMP
pH 7.5, 30C
Sus scrofa
0.01
-
GMP
pH 7.5, 30C
Rattus norvegicus
0.013
-
8-azaguanosine 5'-monophosphate
pH 7.5, 30C
Sus scrofa
0.018
-
GMP
pH 7.5, 30C
Homo sapiens
0.028
-
dGMP
pH 7.5, 30C
Rattus norvegicus
0.07
-
8-azaguanosine 5'-monophosphate
pH 7.5, 30C
Rattus norvegicus
0.074
-
dGMP
pH 7.5, 30C
Homo sapiens
0.091
-
8-azaguanosine 5'-monophosphate
pH 7.5, 30C
Homo sapiens
0.12
-
ATP
pH 7.5, 30C
Sus scrofa
0.18
-
ATP
pH 7.5, 30C
Rattus norvegicus
0.19
-
ATP
pH 7.5, 30C
Homo sapiens
2.1
-
6-thioguanosine 5'-monophosphate
pH 7.5, 30C
Homo sapiens
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Ca2+
no activator
Homo sapiens
Ca2+
no activator
Rattus norvegicus
Ca2+
no activator
Sus scrofa
K+
activation
Homo sapiens
K+
activation
Rattus norvegicus
K+
activation
Sus scrofa
Li+
partial activity
Sus scrofa
Mg2+
-
Rattus norvegicus
Mg2+
-
Sus scrofa
Mg2+
-
Homo sapiens
Mn2+
requirement
Homo sapiens
Mn2+
requirement
Rattus norvegicus
Mn2+
requirement
Sus scrofa
additional information
-
Homo sapiens
additional information
-
Rattus norvegicus
additional information
no activation by Sr2+ or Cs2+
Sus scrofa
Na+
activation
Sus scrofa
NH4+
activation
Homo sapiens
NH4+
activation
Rattus norvegicus
NH4+
activation
Sus scrofa
Purification (Commentary) (protein specific)
Commentary
Organism
method that includes DEAE-cellulose and Sephadex-75 chromatography
Rattus norvegicus
method that includes DEAE-cellulose and Sephadex-75 chromatography
Sus scrofa
method that includes DEAE-cellulose, Sephadex-75 chromatography and isoelectric focusing
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Sus scrofa
-
brain
-
Rattus norvegicus
-
erythrocyte
-
Homo sapiens
-
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
28
-
-
Sus scrofa
Storage Stability (protein specific)
Storage Stability
Organism
0C, below, in 70% saturated ammonium sulfate, several years
Homo sapiens
0C, below, in 70% saturated ammonium sulfate, several years
Rattus norvegicus
0C, below, in 70% saturated ammonium sulfate, several years
Sus scrofa
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + 6-thioguanosine 5'-monophosphate
-
642688
Homo sapiens
ADP + 8-thioguanosine 5'-diphosphate
-
-
-
?
ATP + 6-thioguanosine 5'-monophosphate
-
642688
Rattus norvegicus
ADP + 8-thioguanosine 5'-diphosphate
-
-
-
?
ATP + 6-thioguanosine 5'-monophosphate
-
642688
Sus scrofa
ADP + 8-thioguanosine 5'-diphosphate
-
-
-
?
ATP + 8-azaguanosine 5'-monophosphate
-
642688
Homo sapiens
ADP + 8-azaguanosine 5'-diphosphate
-
-
-
?
ATP + 8-azaguanosine 5'-monophosphate
-
642688
Rattus norvegicus
ADP + 8-azaguanosine 5'-diphosphate
-
-
-
?
ATP + 8-azaguanosine 5'-monophosphate
-
642688
Sus scrofa
ADP + 8-azaguanosine 5'-diphosphate
-
-
-
?
ATP + dGMP
-
642688
Homo sapiens
ADP + dGDP
-
-
-
r
ATP + dGMP
-
642688
Rattus norvegicus
ADP + dGDP
-
-
-
r
ATP + dGMP
-
642688
Sus scrofa
ADP + dGDP
-
-
-
r
ATP + GMP
specificity
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
specificity
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
specificity
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
nucleoside monophosphate binding site is highly specific for guanine moiety
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
nucleoside monophosphate binding site is highly specific for guanine moiety
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
nucleoside monophosphate binding site is highly specific for guanine moiety
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
deoxyguanosine, guanosine are no acceptor substrates
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
deoxyguanosine, guanosine are no acceptor substrates
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
deoxyguanosine, guanosine are no acceptor substrates
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
6-thio-IMP is no acceptor substrate
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
6-thio-IMP is no acceptor substrate
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
6-thio-IMP is no acceptor substrate
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
XMP is no acceptor substrate
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
XMP is no acceptor substrate
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
XMP is no acceptor substrate
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
AMP is no acceptor substrate
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
AMP is no acceptor substrate
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
AMP is no acceptor substrate
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + GMP
CMP, UMP are no acceptor substrates
642688
Homo sapiens
ADP + GDP
-
-
-
?
ATP + GMP
CMP, UMP are no acceptor substrates
642688
Rattus norvegicus
ADP + GDP
-
-
-
?
ATP + GMP
CMP, UMP are no acceptor substrates
642688
Sus scrofa
ADP + GDP
-
-
-
?
ATP + IMP
very poor substrate
642688
Homo sapiens
ADP + IDP
-
-
-
?
dATP + dGMP
-
642688
Homo sapiens
dADP + dGDP
-
-
-
?
dATP + dGMP
-
642688
Rattus norvegicus
dADP + dGDP
-
-
-
?
dATP + dGMP
-
642688
Sus scrofa
dADP + dGDP
-
-
-
?
dATP + GMP
-
642688
Homo sapiens
dADP + GDP
-
-
-
?
dATP + GMP
-
642688
Rattus norvegicus
dADP + GDP
-
-
-
?
dATP + GMP
-
642688
Sus scrofa
dADP + GDP
-
-
-
?
Temperature Optimum [C] (protein specific)
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
30
-
assay at
Homo sapiens
30
-
assay at
Rattus norvegicus
30
-
assay at
Sus scrofa
Temperature Stability [C] (protein specific)
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
30
-
at least 15 min stable from pH 5.5-8.5
Sus scrofa
50
-
10 min, inactivation
Homo sapiens
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
5.5
8.5
at least 15 min stable at 30C
Sus scrofa
pI Value (protein specific)
Organism
Commentary
pI Value Maximum
pI Value
Rattus norvegicus
3 isoelectric variants, predominant form: pI 4.9, agarose gel electrophoresis and isoelectric focusing
4.8
4.7
Homo sapiens
4 isoelectric variants, agarose gel electrophoresis and isoelectric focusing
-
4.9
Other publictions for EC 2.7.4.8
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
738145
Jain
Insights into open/closed conf ...
Homo sapiens
Eur. Biophys. J.
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2016
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739667
Zhang
Mechanistic insight into the f ...
Saccharomyces cerevisiae
Sci. Rep.
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2015
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738614
Nomura
Diversity in guanosine 3,5-bis ...
Arabidopsis thaliana, Bacillus subtilis, Escherichia coli, Oryza sativa Japonica Group, Oryza sativa Japonica Group Nipponbare, Pisum sativum, Saccharomyces cerevisiae, Synechococcus elongatus
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739240
Gupta
Purification and characterizat ...
Brugia malayi
Parasitology
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2014
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737590
Mori
Crystal structure of the guany ...
Homo sapiens
Biochem. Biophys. Res. Commun.
435
334-338
2013
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723031
Dembowski
Alternative splicing of a nove ...
Homo sapiens
J. Nucleic Acids
2012
816237
2012
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721551
Mertlikova-Kaiserova
Point mutations in human guany ...
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2011
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722117
Zhu
Guanylate kinase domains of th ...
Homo sapiens, Rattus norvegicus
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30
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2011
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723014
Kandeel
Binding dynamics and energetic ...
Plasmodium falciparum
J. Mol. Recognit.
24
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2011
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700079
Kandeel
Molecular cloning, expression, ...
Plasmodium falciparum
Mol. Biochem. Parasitol.
159
130-133
2008
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700475
Gardoni
Postsynaptic density-membrane ...
Homo sapiens, Mus musculus, Rattus norvegicus
Neuroscience
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324-333
2008
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700950
Gonzalez-Gutierrez
The guanylate kinase domain of ...
Rattus norvegicus
Proc. Natl. Acad. Sci. USA
105
14198-14203
2008
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672643
Choi
Guanylate kinase, induced fit, ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Biophys. J.
92
1651-1658
2007
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675510
Sumita
Synaptic scaffolding molecule ...
Rattus norvegicus
J. Neurochem.
100
154-166
2007
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676138
Reese
The guanylate kinase domain of ...
Rattus norvegicus
Nat. Struct. Mol. Biol.
14
155-163
2007
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700744
Sugimoto
The rice nuclear gene, VIRESCE ...
Oryza sativa
Plant J.
52
512-527
2007
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671155
El Omari
Structure of Staphylococcus au ...
Staphylococcus aureus
Acta Crystallogr. Sect. F
F62
949-953
2006
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672440
Hible
Crystal structures of GMP kina ...
Escherichia coli
Biochimie
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1157-1164
2006
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673847
Willmon
A guanylate kinase/HSV-1 thymi ...
Homo sapiens, Mus musculus
Gene Ther.
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2006
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Abergel
Impact of the excision of an a ...
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2006
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Hible
Calorimetric and crystallograp ...
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A novel Escherichia coli strai ...
Escherichia coli, Escherichia coli TS202A
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662176
Olsen
Functional analysis of the nuc ...
Rattus norvegicus, Saccharomyces cerevisiae
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642707
Sekulic
Structural characterization of ...
Mus musculus
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642705
Blaszczyk
Crystal structure of unligated ...
Saccharomyces cerevisiae
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642706
Stolworthy
The mouse guanylate kinase dou ...
Mus musculus
Protein Eng.
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745202
Adams
Key role for sulfur in peptid ...
Pyrococcus furiosus
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2001
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642704
Miller
Phosphorylation of ganciclovir ...
Homo sapiens, Sus scrofa
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642703
Prinz
Binding of nucleotides to guan ...
Homo sapiens
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642702
Zhang
Structural and functional role ...
Saccharomyces cerevisiae
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1
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3
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Stehle
Refined structure of the compl ...
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2
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3
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6
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Stehle
Three-dimensional structure of ...
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1
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642694
Le Floc'h
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Purification and properties of ...
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6
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3
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642691
Berger
Guanylate kinase from Saccharo ...
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1
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2
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1
2
5
1
1
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1
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Hall
Purification and properties of ...
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2
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2
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1
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2
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2
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10
1
1
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Boehme
Phosphorylation of the antivir ...
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Moriguchi
Purification and properties of ...
Saccharomyces cerevisiae
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1
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1
3
5
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1
1
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642687
Oeschger
Guanylate kinase from Escheric ...
Escherichia coli, Escherichia coli B / ATCC 11303
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1
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1
1
8
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1
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1
1
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Agarwal
Guanylate kinases from human e ...
Homo sapiens, Rattus norvegicus, Sus scrofa
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483-490
1978
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3
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2
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1
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12
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20
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1
3
37
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3
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2
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1
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Agarwal
Inhibition of rat hepatic guan ...
Rattus norvegicus
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Shimono
Metabolism of deoxyribonucleot ...
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1971
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22
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27
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Buccino
Partial purification and prope ...
Rattus norvegicus
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1
2
15
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Hiraga
Nucleoside monophosphokinases ...
Escherichia coli, Escherichia coli JE24F+
Biochim. Biophys. Acta
114
416-418
1966
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642684
Griffith
The partial purification of de ...
Mus musculus
Biochim. Biophys. Acta
108
114-124
1965
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