Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(6R)-6-[(2E)-4-oxo-6-phenylhex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one | lactone isolated from Cryptocarya rugulosa, covalent inhibition | Staphylococcus aureus | |
(6R)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one | derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition | Staphylococcus aureus | |
(6S)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]tetrahydro-2H-pyran-2-one | derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | P66915 | bifunctional hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.014 | - |
pH not specified in the publication, temperature not specified in the publication | Staphylococcus aureus | (6R)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one | |
0.025 | - |
pH not specified in the publication, temperature not specified in the publication | Staphylococcus aureus | (6R)-6-[(2E)-4-oxo-6-phenylhex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one | |
0.032 | - |
pH not specified in the publication, temperature not specified in the publication | Staphylococcus aureus | (6S)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]tetrahydro-2H-pyran-2-one |