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Literature summary for 2.7.4.6 extracted from

  • Shi, X.Z.; Zhao, X.F.; Wang, J.X.
    Molecular cloning and analysis of function of nucleoside diphosphate kinase (NDPK) from the scallop Chlamys farreri (2008), Biochemistry (Moscow), 73, 686-692.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene Cf-ndpk, DNA and amino acid sequence determination and analysis, sequence comparison, functional expression in Escherichia coli, the recombinant enzyme shows transfer of the terminal phosphate between UDP and ATP Azumapecten farreri

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Azumapecten farreri

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + UDP Azumapecten farreri NDPK regulates a variety of eukaryotic cellular activities including cell proliferation, development, and differentiation ADP + UTP
-
r
NTP + NDP Azumapecten farreri NDPK is a key metabolic enzyme that catalyzes the synthesis of non-adenine nucleoside triphosphate by transferring the terminal phosphate between NDP and NTP NDP + NTP
-
r

Organism

Organism UniProt Comment Textmining
Azumapecten farreri A2TLM3 gene Cf-ndpk
-

Source Tissue

Source Tissue Comment Organism Textmining
adductor
-
Azumapecten farreri
-
digestive gland
-
Azumapecten farreri
-
foot
-
Azumapecten farreri
-
gill
-
Azumapecten farreri
-
gonad
-
Azumapecten farreri
-
hemocyte the expression level is increased in hemocytes after bacterial challenge Azumapecten farreri
-
hemolymph the expression level is increased in hemolymph after bacterial challenge Azumapecten farreri
-
mantle
-
Azumapecten farreri
-
additional information in situ hybridization Azumapecten farreri
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Azumapecten farreri

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + UDP
-
Azumapecten farreri ADP + UTP
-
r
ATP + UDP NDPK regulates a variety of eukaryotic cellular activities including cell proliferation, development, and differentiation Azumapecten farreri ADP + UTP
-
r
NTP + NDP
-
Azumapecten farreri NDP + NTP
-
r
NTP + NDP NDPK is a key metabolic enzyme that catalyzes the synthesis of non-adenine nucleoside triphosphate by transferring the terminal phosphate between NDP and NTP Azumapecten farreri NDP + NTP
-
r

Synonyms

Synonyms Comment Organism
NDPK
-
Azumapecten farreri
nucleoside diphosphate kinase
-
Azumapecten farreri

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Azumapecten farreri

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Azumapecten farreri

pH Stability

pH Stability pH Stability Maximum Comment Organism
3.5
-
below, inactivation Azumapecten farreri

Cofactor

Cofactor Comment Organism Structure
ATP
-
Azumapecten farreri