KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.7 | - |
diphosphoinositol pentakisphosphate | pH 6.8, 37°C | Rattus norvegicus | |
1.39 | - |
ADP | pH 6.8, 37°C | Rattus norvegicus | |
1.89 | - |
ATP | pH 6.8, 37°C | Rattus norvegicus | |
1.94 | - |
1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | pH 6.8, 37°C | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
56000 | - |
SDS-PAGE | Rattus norvegicus |
60000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-diphospho-1D-myo-inositol-pentakisphosphate | Rattus norvegicus | - |
ADP + bis(diphospho)-1D-myo-inositol tetrakisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Sprague-Dawley | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Storage Stability | Organism |
---|---|
-20°C, 50% loss of activity in 20% glycerol after 1 week | Rattus norvegicus |
-70°C, no loss of activity in 20% glycerol for 3 months | Rattus norvegicus |
4°C, complete loss of activity within 18 h | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
Rattus norvegicus | ATP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate | - |
? | |
ADP + diphosphoinositol pentakisphosphate | enzyme has ATP synthase activity | Rattus norvegicus | ATP + ? | - |
? | |
ATP + 5-diphospho-1D-myo-inositol-pentakisphosphate | - |
Rattus norvegicus | ADP + bis(diphospho)-1D-myo-inositol tetrakisphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 56000, SDS-PAGE | Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Rattus norvegicus |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | 40 | 70% activity at 25°C and 40°C | Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
4 | - |
complete loss of activity within 18 h | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.8 | - |
- |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 8.5 | half maximal acitvity at pH 5.5 and pH 8.5 | Rattus norvegicus |