Cloned (Comment) | Organism |
---|---|
gene vip1, phylogenetic analysis, AtVip1 restores InsP7 synthesis in a Saccharomyces cerevisiae kcs1 mutant | Arabidopsis thaliana |
gene vip2, phylogenetic analysis, AtVip2 restores InsP7 synthesis in a Saccharomyces cerevisiae kcs1 mutant | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
D292A | site-directed mutagenesis, inactive mutant | Arabidopsis thaliana |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate | Arabidopsis thaliana | - |
ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate | Arabidopsis thaliana Col-0 | - |
ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 5-diphosphate 2,3,4,5,6-pentakisphosphate | Arabidopsis thaliana | - |
ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 5-diphosphate 2,3,4,5,6-pentakisphosphate | Arabidopsis thaliana Col-0 | - |
ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol hexakisphosphate | Arabidopsis thaliana | - |
ADP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate | - |
? | |
ATP + 1D-myo-inositol hexakisphosphate | Arabidopsis thaliana Col-0 | - |
ADP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Arabidopsis thaliana Col-0 | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Arabidopsis thaliana | - |
root | - |
Arabidopsis thaliana | - |
seed | - |
Arabidopsis thaliana | - |
seedling | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate | - |
Arabidopsis thaliana | ADP + 1D-myo-inositol 1,3-bis(diphosphate) 2,4,5,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate | - |
Arabidopsis thaliana Col-0 | ADP + 1D-myo-inositol 1,3-bis(diphosphate) 2,4,5,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate | - |
Arabidopsis thaliana | ADP + 1D-myo-inositol 1-triphosphate 2,3,4,5,6-pentakisphosphate | - |
? | |
ATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate | - |
Arabidopsis thaliana Col-0 | ADP + 1D-myo-inositol 1-triphosphate 2,3,4,5,6-pentakisphosphate | - |
? | |
ATP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate | - |
Arabidopsis thaliana | ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate | - |
Arabidopsis thaliana Col-0 | ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 5-diphosphate 2,3,4,5,6-pentakisphosphate | - |
Arabidopsis thaliana | ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 5-diphosphate 2,3,4,5,6-pentakisphosphate | - |
Arabidopsis thaliana Col-0 | ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol hexakisphosphate | - |
Arabidopsis thaliana | ADP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate | - |
? | |
ATP + 1D-myo-inositol hexakisphosphate | - |
Arabidopsis thaliana Col-0 | ADP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate | - |
? | |
ATP + 1D-myo-inositol hexakisphosphate | - |
Arabidopsis thaliana | ADP + 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | Vip1 domain organization | Arabidopsis thaliana |
More | Vip2 domain organization | Arabidopsis thaliana |
Synonyms | Comment | Organism |
---|---|---|
AtVip1 | - |
Arabidopsis thaliana |
AtVip2 | - |
Arabidopsis thaliana |
InsP6 kinase | - |
Arabidopsis thaliana |
IP6K | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
additional information | a small amount of InsP7 and InsP8 is accumulated in seeds of higher plants. Residue D292 of AtVIP1 is critical for activity of the kinase domain. The kinase domains alone does not show InsP7 synthesis activity to same levels as the intact AtVIP1 | Arabidopsis thaliana |
additional information | a small amount of InsP7 and InsP8 is accumulated in seeds of higher plants. The kinase domains alone does not show InsP7 synthesis activity to same levels as the intact AtVIP2 | Arabidopsis thaliana |
physiological function | isozymes AtVip1 and AtVip2 are differentially expressed in plant tissues, suggesting nonredundant or non-overlapping functions in plants. Both AtVip1 and AtVip2 encode proteins capable of restoring InsP7 synthesis in Saccharomyces cerevisiae mutants, AtVip1 and AtVip2 can function as bonafide InsP6 kinases. The plant paralogues of the yeast Vip genes can catalyze the synthesis of InsP7 and correct the phenotypic consequences of a yeast vip1 null mutation | Arabidopsis thaliana |
physiological function | isozymes AtVip1 and AtVip2 are differentially expressed in plant tissues, suggesting nonredundant or non-overlapping functions in plants. Both AtVip1 and AtVip2 encode proteins capable of restoring InsP7 synthesis in yeast mutants, thus AtVip1 and AtVip2 can function as bonafide InsP6 kinases. The plant paralogues of the Saccharomyces cerevisiae Vip genes can catalyze the synthesis of InsP7 and correct the phenotypic consequences of a yeast vip1 null mutation | Arabidopsis thaliana |