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Literature summary for 2.7.4.21 extracted from

  • Jadav, R.S.; Kumar, D.; Buwa, N.; Ganguli, S.; Thampatty, S.R.; Balasubramanian, N.; Bhandari, R.
    Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice (2016), Cell. Signal., 28, 1124-1136.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.4.21

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 x * 55000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1D-myo-inositol hexakisphosphate Mus musculus
-
 ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q6PD10
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MEF cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1D-myo-inositol hexakisphosphate
-
 Mus musculus ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 55000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
inositol hexakisphosphate kinase 1
-
 Mus musculus
IP6K1
-
 Mus musculus

General Information

General Information Comment Organism
malfunction enzyme deletion reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma Mus musculus
physiological function the enzyme is involved in early cytoskeleton remodeling events during cancer progression and essential for 4-nitroquinoline-1-oxide-induced invasive carcinoma Mus musculus