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Literature summary for 2.7.4.18 extracted from

  • Shechter, I.
    Phosphate transfer from trans-farnesyl triphosphate to AMP in Gibberella fujikuroi (1974), Biochim. Biophys. Acta, 362, 233-244.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
phosphoenolpyruvate weak Fusarium fujikuroi

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0118
-
trans-farnesyl triphosphate pH 7.6, 35°C, reaction with AMP Fusarium fujikuroi

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ absolute requirement for reaction AMP + trans-farnesyl triphosphate, Mn2+ is ineffective in this reaction Fusarium fujikuroi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
AMP + trans-farnesyl triphosphate Fusarium fujikuroi possible physiological role in biosynthesis of C15 and higher terpenoids in Gibberella fujikuroi ?
-
?

Organism

Organism UniProt Comment Textmining
Fusarium fujikuroi
-
LiLy-I
-
Fusarium fujikuroi LiLy-I
-
LiLy-I
-

Storage Stability

Storage Stability Organism
-70°C, liquid N2 Fusarium fujikuroi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxy-adenosine 5'-phosphate + trans-farnesyl diphosphate 24.1% of the activity with ATP Fusarium fujikuroi 2'-deoxyadenosine + trans-farnesyl triphosphate
-
?
2'-deoxy-uridine 5'-phosphate + trans-farnesyl diphosphate 6% of the activity with ATP Fusarium fujikuroi 2'-deoxyuridine + trans-farnesyl triphosphate
-
?
ADP + trans-farnesyl diphosphate 5'-ADP, 32% of activity compared to ATP Fusarium fujikuroi AMP + trans-farnesyl triphosphate
-
?
ADP + trans-farnesyl diphosphate 5'-ADP, 32% of activity compared to ATP Fusarium fujikuroi LiLy-I AMP + trans-farnesyl triphosphate
-
?
AMP + trans-farnesyl triphosphate
-
Fusarium fujikuroi ADP + ATP + trans-farnesyl diphosphate ADP and ATP are produced when the reaction is performed in the presence of AMP. ADP is the immediate product of the reaction. The formation of ATP is a second order reaction with respect to farnesyl triphosphate and lags the formation of ADP r
AMP + trans-farnesyl triphosphate
-
Fusarium fujikuroi LiLy-I ADP + ATP + trans-farnesyl diphosphate ADP and ATP are produced when the reaction is performed in the presence of AMP. ADP is the immediate product of the reaction. The formation of ATP is a second order reaction with respect to farnesyl triphosphate and lags the formation of ADP r
AMP + trans-farnesyl triphosphate 5'-AMP, 82.8% of the activity with ATP Fusarium fujikuroi ADP + trans-farnesyl diphosphate
-
?
AMP + trans-farnesyl triphosphate 5'-AMP, 82.8% of the activity with ATP Fusarium fujikuroi LiLy-I ADP + trans-farnesyl diphosphate
-
?
AMP + trans-farnesyl triphosphate possible physiological role in biosynthesis of C15 and higher terpenoids in Gibberella fujikuroi Fusarium fujikuroi ?
-
?
ATP + trans-farnesyl diphosphate
-
Fusarium fujikuroi ADP + trans-farnesyl triphosphate
-
r
ATP + trans-farnesyl diphosphate
-
Fusarium fujikuroi LiLy-I ADP + trans-farnesyl triphosphate
-
r
CMP + trans-farnesyl diphosphate 10% of the activity with ATP Fusarium fujikuroi GDP + trans-farnesyl triphosphate
-
?
CMP + trans-farnesyl diphosphate 10% of the activity with ATP Fusarium fujikuroi LiLy-I GDP + trans-farnesyl triphosphate
-
?
GMP + trans-farnesyl diphosphate 8.5% of the activity with ATP Fusarium fujikuroi CDP + trans-farnesyl triphosphate
-
?