Literature summary for 2.7.3.9 extracted from

Mizrachi Nebenzahl, Y.; Blau, K.; Kushnir, T.; Shagan, M.; Portnoi, M.; Cohen, A.; Azriel, S.; Malka, I.; Adawi, A.; Kafka, D.; Dotan, S.; Guterman, G.; Troib, S.; Fishilevich, T.; Gershoni, J.M.; Braiman, A.; Mitchell, A.M.; Mitchell, T.J.; Porat, N.; Goliand, I.; Chalifa Caspi, V.; Swiatlo, E.; Tal,
Streptococcus pneumoniae cell-wall-localized phosphoenolpyruvate protein phosphotransferase can function as an adhesin identification of its host target molecules and evaluation of its potential as a vaccine (2016), PLoS ONE, 11, e0150320 .

Application

Application	Comment	Organism
medicine	recombinant enzyme and anti-enzyme antiserum inhibit adhesion of Streptococcus pneumoniae to cultured human lung adenocarcinoma A-549 cells	Streptococcus pneumoniae

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Streptococcus pneumoniae

Localization	Comment	Organism	GeneOntology No.	Textmining
cell wall	-	Streptococcus pneumoniae	5618	-

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
120091	-	MALDI-TOF mass spectrometry	Streptococcus pneumoniae

Organism	UniProt	Comment	Textmining
Streptococcus pneumoniae	-	-	-
Streptococcus pneumoniae TIGR 4	-	-	-
Streptococcus pneumoniae WU2	-	-	-

Purification (Comment)	Organism
-	Streptococcus pneumoniae
ammonium sulfate precipitation and Superdex S200 gel filtration	Streptococcus pneumoniae

Subunits	Comment	Organism
homodimer	2 * 72000, SDS-PAGE	Streptococcus pneumoniae
homodimer	2 * 63165, calculated from amino acid sequence	Streptococcus pneumoniae
homodimer	2 * 65400, calculated from amino acid sequence	Streptococcus pneumoniae
homodimer	2 * 75000, HAT-tagged enzyme, SDS-PAGE	Streptococcus pneumoniae

Synonyms	Comment	Organism
ptsA	-	Streptococcus pneumoniae

General Information	Comment	Organism
physiological function	surface-localized enzyme functions as an adhesin for target host cells	Streptococcus pneumoniae