Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phosphoenolpyruvate | physiological concentrations of phosphoenolpyruvate and Mg2+ increase the amount of dimeric, active dephospho-enzyme I | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
H189A | inactive enzyme form | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
pyruvate | physiological concentrations of pyruvate and Mg2+ decrease the amount of dimeric, active dephospho-enzyme I | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | enzyme I of the PEP:sugar phosphotransferase system is regulated by a monomer-dimer equilibrium. A Mg2+-dependent autophosphorylation by phosphoenolpyruvate requires the homodimer. Physiological concentrations of phosphoenolpyruvate and Mg2+ increase, whereas pyruvate and Mg2+ decrease the amount of dimeric, active dephospho-enzyme I | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Subunits | Comment | Organism |
---|---|---|
More | enzyme I of the PEP:sugar phosphotransferase system is regulated by a monomer-dimer equilibrium. A Mg2+-dependent autophosphorylation by phosphoenolpyruvate requires the homodimer. Physiological concentrations of phosphoenolpyruvate and Mg2+ increase, whereas pyruvate and Mg2+ decrease the amount of dimeric, active dephospho-enzyme I | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
phosphotransferase enzyme I | - |
Escherichia coli |