Literature summary for 2.7.3.2 extracted from

Shin, J.B.; Streijger, F.; Beynon, A.; Peters, T.; Gadzala, L.; McMillen, D.; Bystrom, C.; Van der Zee, C.E.; Wallimann, T.; Gillespie, P.G.
Hair bundles are specialized for ATP delivery via creatine kinase (2007), Neuron, 53, 371-386.

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Protein Variants

Protein Variants	Comment	Organism
additional information	enzyme knockout results in loss of hearing	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Gallus gallus	5829	-

Organism

Organism	UniProt	Comment	Textmining
Gallus gallus	-	-	-
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hair	after beta-actin, cytosolic brain isoform of creatin kinase is the most abundant protein in hair bundle and capable of maintaining high aTP levels despite 1 mM/s ATP consumption by the plasma-membrane Ca2+-ATPase	Gallus gallus	-
hair	creatine kinase circuit is essential for high-sensitivity hearing	Mus musculus	-

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Release 2023.1 (January 2023)