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Literature summary for 2.7.2.1 extracted from
- Acetate kinase from Veillonella alcalescens. Regulation of enzyme activity by succinate and substrates (1976), J. Biol. Chem., 251, 3117-3121.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| succinate | heterotropic allosteric effector, necessary for enzymatic activity in both directions | Veillonella parvula |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.1 | - |
ADP | pH 7.3, 37°C, 1.0 M succinate | Veillonella parvula | |
| 1.3 | - |
ADP | pH 7.3, 37°C, 0.2 M succinate | Veillonella parvula | |
| 3.3 | - |
acetyl phosphate | pH 7.3, 37°C, 2.0 M succinate | Veillonella parvula | |
| 5 | - |
acetyl phosphate | pH 7.3, 37°C, 0.2 M succinate | Veillonella parvula | |
| 9 | - |
ATP | pH 7.3, 37°C, 50 M succinate | Veillonella parvula | |
| 10 | - |
ATP | pH 7.3, 37°C, 5.0 M succinate | Veillonella parvula | |
| 100 | - |
acetate | pH 7.3, 37°C, 50 M succinate | Veillonella parvula | |
| 170 | - |
acetate | pH 7.3, 37°C, 5.0 M succinate | Veillonella parvula | |
| 300 | - |
propionate | pH 7.3, 37°C, 50 M succinate | Veillonella parvula | |
| 1000 | - |
propionate | pH 7.3, 37°C, 5.0 M succinate | Veillonella parvula | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 44000 | - |
2 * 44000, SDS-PAGE | Veillonella parvula |
| 87000 | - |
gel filtration | Veillonella parvula |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetate | Veillonella parvula | - |
ADP + acetyl phosphate | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Veillonella parvula | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 375 | 500 | - |
Veillonella parvula |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetate | - |
Veillonella parvula | ADP + acetyl phosphate | - |
r | |
| ATP + propionate | - |
Veillonella parvula | ADP + propionyl phosphate | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 44000, SDS-PAGE | Veillonella parvula |
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