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Literature summary for 2.7.12.2 extracted from

  • Kumar, K.; Sinha, A.K.
    Overexpression of constitutively active mitogen activated protein kinase kinase 6 enhances tolerance to salt stress in rice (2013), Rice (N.Y.), 6, 25.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene OsMKK6, recombinant expression of enzyme mutant S221E/T227E in transgenic Oryza sativa PB1 plants under the control of constitutive 35S CaMV promoter via transformation into Agrobacterium cells and subsequently into rice Oryza sativa Indica Group

Protein Variants

Protein Variants Comment Organism
S221E/T227E OsMKK6 is made constitutively active by mutating serine and threonine to glutamic acid by site directed mutagenesis, and transformed in indica cultivar rice var. Pusa Basmati-1. The transgenic seedlings growing in 200 mM NaCl solution show increased root/shoot length and weight, less chlorophyll beaching and higher MAPK activity compared to the wild-type. Phenotypes, overview Oryza sativa Indica Group

Organism

Organism UniProt Comment Textmining
Oryza sativa Indica Group Q0Z7Z4 var. Pusa Basmati-1
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Source Tissue

Source Tissue Comment Organism Textmining
culm
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Oryza sativa Indica Group
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leaf
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Oryza sativa Indica Group
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additional information analysis of OsMKK6 expression profile in subsp. japonica. Among tissue specific expression OsMKK6 shows highest expression level in panicle followed by leaves, roots and least in culms. Transcript of OsMKK6 is noticed in almost all the tissue and its accumulation is highest in mature roots Oryza sativa Indica Group
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panicle
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Oryza sativa Indica Group
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root
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Oryza sativa Indica Group
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Synonyms

Synonyms Comment Organism
MAPKK
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Oryza sativa Indica Group
mitogen activated protein kinase kinase 6
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Oryza sativa Indica Group
OsMKK6
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Oryza sativa Indica Group

Expression

Organism Comment Expression
Oryza sativa Indica Group salt and cold stresses upregulate expression of OsMKK6. OsMKK6 shows more transcript accumulation in both roots and leaves in salt stress whereas in cold stress transcript accumulation is higher in roots but shows less accumulation of transcript in drought stressed leaves up

General Information

General Information Comment Organism
metabolism the mitogen activated protein kinase (MAPK) kinase (MKK) is a key component of MAPK cascade that plays important roles in intra and extra cellular signaling in plants Oryza sativa Indica Group
physiological function role of OsMKK6 gene in salt stress signaling in rice. Constitutively active OsMKK6 overexpressing rice plants exhibit higher salt stress tolerance, overview Oryza sativa Indica Group