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Literature summary for 2.7.12.2 extracted from

  • Irie, K.; Takase, M.; Lee, K.S.; Levin, D.E.; Araki, H.; Matsumoto, K.; Oshima, Y.
    MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C (1993), Mol. Cell. Biol., 13, 3076-3083.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + protein Saccharomyces cerevisiae MKK1 and MKK2 function in a signal transduction pathway involving the protein kinases encoded by PKC1, BCK1, and MPK1. The site of action for MKK1 and MKK2 is between BCK1 and MPK1 ADP + phosphoprotein
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P32490
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Saccharomyces cerevisiae P32491
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + protein MKK1 and MKK2 function in a signal transduction pathway involving the protein kinases encoded by PKC1, BCK1, and MPK1. The site of action for MKK1 and MKK2 is between BCK1 and MPK1 Saccharomyces cerevisiae ADP + phosphoprotein
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Synonyms

Synonyms Comment Organism
MAP kinase kinase MKK1/SSP32
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Saccharomyces cerevisiae
MAP kinase kinase MKK2/SSP33
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Saccharomyces cerevisiae