Literature summary for 2.7.12.2 extracted from

Derijard, B.; Raingeaud, J.; Barrett, T.; Wu, I.H.; Han, J.; Ulevitch, R.J.; Davis, R.J.
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms (1995), Science, 267, 682-685.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + protein	Homo sapiens	-	ADP + phosphoprotein	-	?
ATP + protein	Homo sapiens	enzyme is involved in independent human MAP-kinase signal transduction pathway	ADP + phosphoprotein	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P45985	-	-
Homo sapiens	P46734	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + protein	-	Homo sapiens	ADP + phosphoprotein	-	?
ATP + protein	enzyme is involved in independent human MAP-kinase signal transduction pathway	Homo sapiens	ADP + phosphoprotein	-	?

Synonyms

Synonyms	Comment	Organism
dual specificity mitogen-activated protein kinase kinase 3	-	Homo sapiens
dual specificity mitogen-activated protein kinase kinase 4	-	Homo sapiens

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Release 2023.1 (January 2023)