Literature summary for 2.7.11.9 extracted from

Granero, F.; Revert, F.; Revert-Ros, F.; Lainez, S.; Martinez-Martinez, P.; Saus, J.
A human-specific TNF-responsive promoter for Goodpasture antigen-binding protein (2005), FEBS J., 272, 5291-5305.

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	expression of the Goodpasture antigen-binding protein is induced by tumor necrosis factor	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
DNA sequence determination and analysis, a TNF-responsive transcription unit that locates the enzyme in the signalling cascade of TNF, regulation of transcription, e.g. by tumor necrosis factor, via cooperation in a bidirectional transcription complex with the gene encoding the DNA polymerase kappa, NFkappaB, and a 140-bp promoter with a Sp1 site and a TATA-like element, promoter analysis, overview	Homo sapiens

Cloned (Comment)

Organism

DNA sequence determination and analysis, a TNF-responsive transcription unit that locates the enzyme in the signalling cascade of TNF, regulation of transcription, e.g. by tumor necrosis factor, via cooperation in a bidirectional transcription complex with the gene encoding the DNA polymerase kappa, NFkappaB, and a 140-bp promoter with a Sp1 site and a TATA-like element, promoter analysis, overview

Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + [Goodpasture antigen-binding protein]	Homo sapiens	autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen, the enzyme is involved in autoimmune processes and disease	ADP + [Goodpasture antigen-binding phosphoprotein]	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9Y5P4	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + [Goodpasture antigen-binding protein]	autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen, the enzyme is involved in autoimmune processes and disease	Homo sapiens	ADP + [Goodpasture antigen-binding phosphoprotein]	-	?
ATP + [Goodpasture antigen-binding protein]	autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen	Homo sapiens	ADP + [Goodpasture antigen-binding phosphoprotein]	-	?

Synonyms

Synonyms	Comment	Organism
goodpasture-antigen-binding protein kinase	-	Homo sapiens
GPBP	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens