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Literature summary for 2.7.11.9 extracted from

  • Raya, A.; Revert-Ros, F.; Martinez-Martinez, P.; Navarro, S.; Rosello, E.; et al.
    Goodpasture antigen-binding protein, the kinase that phosphorylates the goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis (2000), J. Biol. Chem., 275, 40392-40399.
    View publication on PubMed
Search for more literature for 2.7.11.9

Cloned(Commentary)

Cloned (Comment) Organism
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 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + goodpasture antigen Homo sapiens enzyme is involved in autoimmune pathogenesis. Enzyme expression is up-regulated in the striated muscle of a Goodpasture patient and in other autoimmune conditions including cutaneous lupus erythematosus, pemphigoid, and lichen planus ADP + phosphorylated goodpasture antigen
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 ?

Organism

Organism UniProt Comment Textmining
Bos taurus Q9GKI7
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-
Homo sapiens Q9Y5P4
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Mus musculus Q9EQG9
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Source Tissue

Source Tissue Comment Organism Textmining
cell culture HeLa cells Homo sapiens
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additional information enzyme is preferentially expressed in small vessels and histological structures targeted by natural autoimmune responses including alveolar and glomerular basement membranes Bos taurus
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additional information preferential expression in the histological structures that are targets of common autoimmune responses Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + goodpasture antigen phosphorylation in the N-terminal region of the goodpasture antigen Homo sapiens ADP + phosphorylated goodpasture antigen
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 ?
ATP + goodpasture antigen enzyme is involved in autoimmune pathogenesis. Enzyme expression is up-regulated in the striated muscle of a Goodpasture patient and in other autoimmune conditions including cutaneous lupus erythematosus, pemphigoid, and lichen planus Homo sapiens ADP + phosphorylated goodpasture antigen
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 ?

Synonyms

Synonyms Comment Organism
GPBP
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 Homo sapiens