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Literature summary for 2.7.11.7 extracted from

  • Maruta, H.; Korn, E.D.
    Acanthamoeba cofactor protein is a heavy chain kinase required for actin activation of the Mg2+-ATPase activity of Acanthamoeba myosin I (1977), J. Biol. Chem., 252, 8329-8332.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ not required Acanthamoeba castellanii
Mg2+ requirement Acanthamoeba castellanii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + myosin I heavy chain Acanthamoeba castellanii
-
ADP + myosin I heavy chain phosphate
-
?

Organism

Organism UniProt Comment Textmining
Acanthamoeba castellanii
-
myosin I heavy chain kinase
-

Purification (Commentary)

Purification (Comment) Organism
partial Acanthamoeba castellanii

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
Acanthamoeba castellanii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin I heavy chain
-
Acanthamoeba castellanii ADP + myosin I heavy chain phosphate
-
?
ATP + myosin I heavy chain myosin light chains are no substrates Acanthamoeba castellanii ADP + myosin I heavy chain phosphate
-
?

Cofactor

Cofactor Comment Organism Structure
ATP
-
Acanthamoeba castellanii