Cloned (Comment) | Organism |
---|---|
bifunctional protein, expressed from the aceK gene | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [isocitrate dehydrogenase (NADP+)] | Escherichia coli | reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
r | |
ATP + [isocitrate dehydrogenase (NADP+)] | Escherichia coli W3550 | reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
wild-type and mutants | - |
Escherichia coli W3550 | - |
wild-type and mutants | - |
Purification (Comment) | Organism |
---|---|
partial, bifunctional protein | Escherichia coli |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.11 | 0.63 | - |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [isocitrate dehydrogenase (NADP+)] | - |
Escherichia coli | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
r | |
ATP + [isocitrate dehydrogenase (NADP+)] | reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways | Escherichia coli | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
r | |
ATP + [isocitrate dehydrogenase (NADP+)] | - |
Escherichia coli W3550 | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
r | |
ATP + [isocitrate dehydrogenase (NADP+)] | reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways | Escherichia coli W3550 | ADP + [isocitrate dehydrogenase (NADP+)] phosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
IDH kinase/phosphatase | - |
Escherichia coli |