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Literature summary for 2.7.11.31 extracted from

  • Beg, Z.H.; Stonik, J.A.; Brewer, B.
    Human hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase: evidence for the regulation of enzymic activity by a bicyclic phosphorylation cascade (1984), Biochem. Biophys. Res. Commun., 119, 488-498.
    View publication on PubMed
Search for more literature for 2.7.11.31

Activating Compound

Activating Compound Comment Organism Structure
Reductase kinase kinase activation, i.e. EC 2.7.1.110, in the presence of MgATP2- Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Protein phosphatase
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
microsome
-
 Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement, actual substrate: MgATP2- Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)]
-
 Homo sapiens ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Homo sapiens