BRENDA - Enzyme Database show
show all sequences of 2.7.11.30

GsSRK, a G-type lectin S-receptor-like serine/threonine protein kinase, is a positive regulator of plant tolerance to salt stress

Sun, X.L.; Yu, Q.Y.; Tang, L.L.; Ji, W.; Bai, X.; Cai, H.; Liu, X.F.; Ding, X.D.; Zhu, Y.M.; J. Plant Physiol. 170, 505-515 (2013)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
gene GsSRK, DNA and amino acid sequence determination and analysis, quantitative real-time PCR expression analysis, recombinant expression under the control of the strong constitutive CaMV35S promoter in transgenic Arabidopsis thaliana plants transfected using Agrobacterium tumefaciens strain LBA4404. Overexpression of GsSRK in Arabidopsis thaliana enhances plant tolerance to high salinity
Glycine soja
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Glycine soja
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
leaf
-
Glycine soja
-
root
-
Glycine soja
-
seedling
-
Glycine soja
-
Subunits
Subunits
Commentary
Organism
?
x * 93220, sequence calculation
Glycine soja
More
the GsSRK protein has 11 sub domains within the highly conserved kinase catalytic domain (KD, residues 518-787) including protein kinase active sites, ATP binding sites, substrate binding sites, and two activation loops (A-loop, residues 655-661 and residues 676-679). Besides the conserved kinase domain, GsSRK also contains a B lectin (bulb-type mannose-specific lectin) region at the N-terminus, which is involved in recognizing diverse carbohydrates containing mannose and a wide variety of biological processes
Glycine soja
pI Value
Organism
Commentary
pI Value Maximum
pI Value
Glycine soja
sequence calculation
-
6.12
Cloned(Commentary) (protein specific)
Commentary
Organism
gene GsSRK, DNA and amino acid sequence determination and analysis, quantitative real-time PCR expression analysis, recombinant expression under the control of the strong constitutive CaMV35S promoter in transgenic Arabidopsis thaliana plants transfected using Agrobacterium tumefaciens strain LBA4404. Overexpression of GsSRK in Arabidopsis thaliana enhances plant tolerance to high salinity
Glycine soja
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
leaf
-
Glycine soja
-
root
-
Glycine soja
-
seedling
-
Glycine soja
-
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 93220, sequence calculation
Glycine soja
More
the GsSRK protein has 11 sub domains within the highly conserved kinase catalytic domain (KD, residues 518-787) including protein kinase active sites, ATP binding sites, substrate binding sites, and two activation loops (A-loop, residues 655-661 and residues 676-679). Besides the conserved kinase domain, GsSRK also contains a B lectin (bulb-type mannose-specific lectin) region at the N-terminus, which is involved in recognizing diverse carbohydrates containing mannose and a wide variety of biological processes
Glycine soja
pI Value (protein specific)
Organism
Commentary
pI Value Maximum
pI Value
Glycine soja
sequence calculation
-
6.12
Expression
Organism
Commentary
Expression
Glycine soja
the enzyme is induced by salt and drought stresses and by abscisic acid, its expression increases in both roots and leaves. Abascisic acid induction of GsSRK expression does not mimic the induction obtained by salt and drought stresses, particularly in roots, which strongly indicates that GsSRK regulates plant tolerance to salt and drought stresses through an abscisic acid-independent pathway
up
General Information
General Information
Commentary
Organism
physiological function
GsSRK, a G-type lectin S-receptor-like serine/threonine protein kinase, is a positive regulator of plant tolerance to salt stress. GsSRK might be involved also in drought, and possibly other osmotic stress signaling transduction
Glycine soja
General Information (protein specific)
General Information
Commentary
Organism
physiological function
GsSRK, a G-type lectin S-receptor-like serine/threonine protein kinase, is a positive regulator of plant tolerance to salt stress. GsSRK might be involved also in drought, and possibly other osmotic stress signaling transduction
Glycine soja
Expression (protein specific)
Organism
Commentary
Expression
Glycine soja
the enzyme is induced by salt and drought stresses and by abscisic acid, its expression increases in both roots and leaves. Abascisic acid induction of GsSRK expression does not mimic the induction obtained by salt and drought stresses, particularly in roots, which strongly indicates that GsSRK regulates plant tolerance to salt and drought stresses through an abscisic acid-independent pathway
up
Other publictions for EC 2.7.11.30
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
740796
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740900
Sun
GsSRK, a G-type lectin S-recep ...
Glycine soja
J. Plant Physiol.
170
505-515
2013
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Lab. Invest.
89
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Insulin gene is a target in ac ...
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Biochem. Biophys. Res. Commun.
377
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2008
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691269
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Synthesis and biological evalu ...
Rattus norvegicus
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18
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2008
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691460
Zhou
Inhibition of the TGF-beta rec ...
Homo sapiens
Blood
112
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2008
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691532
Xu
TGF-beta receptor kinase inhib ...
Homo sapiens
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142
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2008
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691833
Fujiwara
Implications of mutations of a ...
Homo sapiens
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692159
Bueno
Semi-mechanistic modelling of ...
Homo sapiens
Eur. J. Cancer
44
142-150
2008
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693034
Zhao
Smad4-dependent TGF-beta signa ...
Homo sapiens
J. Biol. Chem.
283
11293-11301
2008
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693381
Young
The activin receptor-like kina ...
Ovis aries
J. Endocrinol.
196
251-261
2008
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694090
Xu
Cyclin G2 is degraded through ...
Homo sapiens
Mol. Biol. Cell
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4968-4979
2008
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706906
Li
Down-regulation of transformin ...
Homo sapiens
World J. Gastroenterol.
14
2894-2899
2008
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664721
Zhang
Activin receptor-like kinase 7 ...
Rattus norvegicus
Diabetologia
49
506-518
2006
3
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664088
Peng
Kinetic characterization of no ...
Homo sapiens
Biochemistry
44
2293-2304
2005
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664715
Desgrosellier
Activin receptor-like kinase 2 ...
Gallus gallus
Dev. Biol.
280
201-210
2005
1
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665640
Ungefroren
Transforming growth factor-bet ...
Homo sapiens
J. Biol. Chem.
280
2644-2652
2005
1
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665699
Lux
Human retroviral gag- and gag- ...
Homo sapiens
J. Biol. Chem.
280
8482-8493
2005
1
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1
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1
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666443
Halder
A specific inhibitor of TGF-be ...
Homo sapiens
Neoplasia
7
509-521
2005
1
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1
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663984
Ge
Selective inhibitors of type I ...
Homo sapiens
Biochem. Pharmacol.
68
41-50
2004
2
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1
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1
1
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2
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3
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3
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3
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1
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1
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1
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2
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1
1
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1
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1
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3
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3
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1
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1
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664036
Ottesen
Semisynthesis of phosphovarian ...
Homo sapiens
Biochemistry
43
5698-5706
2004
2
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1
2
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2
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2
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4
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1
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1
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1
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2
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4
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1
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1
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664318
Sawyer
Synthesis and activity of new ...
Homo sapiens, Mus musculus
Bioorg. Med. Chem. Lett.
14
3581-3584
2004
2
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1
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6
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2
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2
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2
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1
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2
-
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2
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2
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2
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2
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6
2
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1
2
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6
6
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2
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2
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1
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2
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2
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2
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2
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-
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665532
Kim
Activin receptor-like kinase-7 ...
Homo sapiens
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2004
1
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1
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3
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1
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1
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3
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2
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5
-
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1
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1
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1
1
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3
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1
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5
-
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665554
Yakymovych
Smad2 phosphorylation by type ...
Mus musculus
J. Biol. Chem.
279
35781-35787
2004
1
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1
2
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2
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1
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2
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5
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1
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1
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1
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1
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1
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1
2
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2
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2
-
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5
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1
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-
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1
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-
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666283
Forrester
Tegumental expression of a nov ...
Schistosoma mansoni
Mol. Biochem. Parasitol.
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149-156
2004
-
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1
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1
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3
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4
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1
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1
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4
-
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-
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666359
Mazerbourg
Growth differentiation factor- ...
Rattus norvegicus
Mol. Endocrinol.
18
653-665
2004
2
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1
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1
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2
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1
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3
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2
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3
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4
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1
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2
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1
1
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1
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3
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4
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664282
Roberts
Identification of novel isofor ...
Homo sapiens
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68
1719-1726
2003
2
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1
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1
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1
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2
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8
-
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2
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1
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1
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1
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8
-
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665481
Liu
Smads 2 and 3 are differential ...
Rattus norvegicus
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2003
1
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5
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1
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5
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665487
Harrison
Identification of a functional ...
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278
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2003
2
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1
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27
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1
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1
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1
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-
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1
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1
1
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-
-
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1
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2
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1
1
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27
-
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1
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1
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1
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1
1
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666312
Goumans
Activin receptor-like kinase ( ...
Mus musculus
Mol. Cell
12
817-828
2003
2
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1
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1
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1
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1
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1
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1
1
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5
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1
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2
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1
1
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1
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5
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1
1
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5
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666512
Fink
TGF-beta-induced nuclear local ...
Homo sapiens
Oncogene
22
1317-1323
2003
1
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1
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3
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5
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1
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1
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5
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