Protein Variants | Comment | Organism |
---|---|---|
Y216F | inactive | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Protein kinase C | protein kinase C inhibits GSK-3beta by phosphorylating its auto-inhibitory domain at Ser9 | Rattus norvegicus | |
SB216763 | potent and selective cell permeable ATP-competitive inhibitor of GSK3 | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
glycogen synthase kinase-3beta | - |
Rattus norvegicus |
GSK-3beta | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000034 | - |
- |
Rattus norvegicus | SB216763 |
General Information | Comment | Organism |
---|---|---|
malfunction | inhibition of GSK-3beta mediates Nrf2 activation by the M1 receptor | Rattus norvegicus |