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Literature summary for 2.7.11.26 extracted from
- A role for glycogen synthase kinase-3 in antagonizing mycobacterial immune evasion by negatively regulating IL-10 induction (2009), J. Leukoc. Biol., 86, 283-291.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | treatment with 1 CFU/cell bacillus Calmette-Guerin increases the phosphorylation of GSK3beta at serine 9 and therefore inhibits the activity to about 40% 1 h after stimulation | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| monocyte | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glycogen synthase kinase-3beta | - |
Homo sapiens |
| GSK-3beta | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens |  |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | GSK3 negatively regulates mycobacteria-induced interleukin-10 production in human monocytes | Homo sapiens |
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Release 2023.1 (January 2023)
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