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Literature summary for 2.7.11.26 extracted from
- Expression and function of glycogen synthase kinase-3 in human hair follicles (2010), Arch. Dermatol. Res., 302, 263-270.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (2'Z,3'E)-6-bromoindirubin-3'-oxime | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hair follicle | - |
Homo sapiens | - |
| hair follicle bulge stem cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + beta-catenin | - |
Homo sapiens | ADP + phosphorylated beta-catenin | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glycogen synthase kinase-3 | - |
Homo sapiens |
| GSK-3 | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | inhibition of glycogen synthase kinase-3 increases beta-catenin concentration in the cytoplasm | Homo sapiens |
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Release 2023.1 (January 2023)
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