Literature summary for 2.7.11.26 extracted from

Ikeda, Y.; Ishiguro, K.; Fujita, S.C.
Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain (2007), FEBS Lett., 581, 891-897.

Search for more literature for 2.7.11.26

Activating Compound

Activating Compound	Comment	Organism	Structure
ether	dramatic increase in the phosphorylation level of Ser9 of TPKI/GSK3beta immediately and 10 min after ether administration, followed by rapid virtual reversion to baseline by 20 min, no significant changes in the protein level or Tyr216 phosphorylation level of the enzyme	Mus musculus
additional information	cold water stress dramatically and transiently increases TPKI/GSK3beta phosphorylation at Ser9 accompanied by Akt phosphorylation	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	inactivating phosphorylation of Ser9 of TPKI/GSK3beta in close correspondence with tau phosphorylation	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	male C57BL/6Njcl mice	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-
hippocampus	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + protein tau	-	Mus musculus	ADP + protein tau phosphate	-	?

Synonyms

Synonyms	Comment	Organism
TPKI/GSK3beta	-	Mus musculus

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Release 2023.1 (January 2023)