Application | Comment | Organism |
---|---|---|
analysis | a concept and implementation of a new simple inhibitor screening method applicable for a broad range of human proteins by using transformed bacteria is reported | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
into the plasmid pRSET-CA for expression in Escherichia coli Bl21DE3 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
K53A | kinase-negative mutant | Homo sapiens |
T106M | inhibitor-insensitive mutant | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
SB202190 | benzyl coumarin derivative | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | Homo sapiens | - |
ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | - |
Homo sapiens |
Purification (Comment) | Organism |
---|---|
GST- and His-tags are used in the purification experiments | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
Homo sapiens | ADP + a phosphoprotein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mitogen-activated kinase | - |
Homo sapiens |
p38 | - |
Homo sapiens |
p38 MAP kinase | - |
Homo sapiens |
p38 mitogen-activated protein kinase | - |
Homo sapiens |
p38 protein | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |