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Literature summary for 2.7.11.24 extracted from

  • Chang, C.H.; Yu, F.Y.; Wang, L.T.; Lin, Y.S.; Liu, B.H.
    Activation of ERK and JNK signaling pathways by mycotoxin citrinin in human cells (2009), Toxicol. Appl. Pharmacol., 237, 281-287.
    View publication on PubMed
Search for more literature for 2.7.11.24

Activating Compound

Activating Compound Comment Organism Structure
citrinin the exposure of HEK-293 and HeLa cells to citrinin results in a dose-dependent increase in the phosphorylation of ERK1/2 and JNK Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
PD98059 MEK1 inhibitor, i.e. 2-(2'-amino-3'-methoxyphenyl)-oxanaphthalen-4-one Homo sapiens
U0126 MEK1/2 inhibitor, i.e. 1,4-diamino-2,3-dicyano-1,4-bis[2-aminophenylthio] butadiene Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
c-Jun N-terminal kinase
-
 Homo sapiens
ERK1/2
-
 Homo sapiens
extracellular signal-related kinase
-
 Homo sapiens
JNK
-
 Homo sapiens
MAPK kinase
-
 Homo sapiens
MEK
-
 Homo sapiens