Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.23 extracted from

  • Xiao, T.; Hall, H.; Kizer, K.O.; Shibata, Y.; Hall, M.C.; Borchers, C.H.; Strahl, B.D.
    Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast (2003), Genes Dev., 17, 654-663.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.23

Cloned(Commentary)

Cloned (Comment) Organism
expression of plasmid-encoded Ctk1 in enzyme-deficient ctk1DELTA mutant strain Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
additional information construction of an enzyme-deficient ctk1DELTA mutant strain which shows selective abolishment of histone H3 Lys36 methylation Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Saccharomyces cerevisiae 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [DNA-directed RNA polymerase] Saccharomyces cerevisiae hyperphosphorylation of the C-terminal domain CTD of the RNA polymerase II large subunit by Ctk1 is essentially required for methylation of histone H3 Lys36 in transcription elongation in volving association of Set2 to the hyperphosphorylated RNA polymerase II, overview ADP + phospho-[DNA-directed RNA polymerase]
-
 ?
ATP + [DNA-directed RNA polymerase] Saccharomyces cerevisiae AS4 hyperphosphorylation of the C-terminal domain CTD of the RNA polymerase II large subunit by Ctk1 is essentially required for methylation of histone H3 Lys36 in transcription elongation in volving association of Set2 to the hyperphosphorylated RNA polymerase II, overview ADP + phospho-[DNA-directed RNA polymerase]
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae AS4
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [DNA-directed RNA polymerase] hyperphosphorylation of the C-terminal domain CTD of the RNA polymerase II large subunit by Ctk1 is essentially required for methylation of histone H3 Lys36 in transcription elongation in volving association of Set2 to the hyperphosphorylated RNA polymerase II, overview Saccharomyces cerevisiae ADP + phospho-[DNA-directed RNA polymerase]
-
 ?
ATP + [DNA-directed RNA polymerase] hyperphosphorylation of the C-terminal domain CTD of the RNA polymerase II large subunit Saccharomyces cerevisiae ADP + phospho-[DNA-directed RNA polymerase]
-
 ?
ATP + [DNA-directed RNA polymerase] hyperphosphorylation of the C-terminal domain CTD of the RNA polymerase II large subunit by Ctk1 is essentially required for methylation of histone H3 Lys36 in transcription elongation in volving association of Set2 to the hyperphosphorylated RNA polymerase II, overview Saccharomyces cerevisiae AS4 ADP + phospho-[DNA-directed RNA polymerase]
-
 ?
ATP + [DNA-directed RNA polymerase] hyperphosphorylation of the C-terminal domain CTD of the RNA polymerase II large subunit Saccharomyces cerevisiae AS4 ADP + phospho-[DNA-directed RNA polymerase]
-
 ?

Synonyms

Synonyms Comment Organism
CTD kinase
-
 Saccharomyces cerevisiae
Ctk1
-
 Saccharomyces cerevisiae
RNA pol II C-terminal domain kinase
-
 Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Saccharomyces cerevisiae