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Literature summary for 2.7.11.23 extracted from

  • Baskaran, R.; Escobar, S.R.; Wang, J.Y.
    Nuclear c-Abl is a COOH-terminal repeated domain (CTD)-tyrosine (CTD)-tyrosine kinase-specific for the mammalian RNA polymerase II: possible role in transcription elongation (1999), Cell Growth Differ., 10, 387-396.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in saos-2 cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
GST-CTD overexpression of this fragment inhibits tyrosine phosphorylation of RNAP II in vivo Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
Mus musculus 5634
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [DNA-directed eukaryotic RNA polymerase II subunit IIa] no substrates are the RNA polymerases II of Drosophila melanogaster and yeast Mus musculus ADP + phospho-[DNA-directed RNA polymerase II subunit IIa]
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