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Literature summary for 2.7.11.22 extracted from

  • Gaamouche, T.; Manes, C.L.; Kwiatkowska, D.; Berckmans, B.; Koumproglou, R.; Maes, S.; Beeckman, T.; Vernoux, T.; Doonan, J.H.; Traas, J.; Inze, D.; De Veylder, L.
    Cyclin-dependent kinase activity maintains the shoot apical meristem cells in an undifferentiated state (2010), Plant J., 64, 26-37.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of the dominant negative allele CDKA;1.N146 of CDKA;1 in transgenic Arabidopsis thaliana plants using Agrobacterium tumefaciens-mediated transformation and the pBIN+ vector with a 3' NOS terminator Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information construction of transgenic plants with transformed dominant negative allele (CDKA;1.N146) of CDKA;1. CDKA;1.N146 expression level in Arabidopsis thaliana affects meristem organization, the number of plants with multiple meristems is much higher in homozygous versus hemizygous PSTM:CDKA;1.N146 populations. The hemizygous PSTM:CDKA;1.N146 plants lose the typical malformed leaf phenotype of the homozygous plants, corresponding with a decrease in the CDKA;1.N146 expression level, and the number of plants with two or more rosettes is significantly reduced, phenotypes, overview Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Arabidopsis thaliana Col-0
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
meristem
-
Arabidopsis thaliana
-
seedling
-
Arabidopsis thaliana
-
shoot apical meristem cells Arabidopsis thaliana
-
shoot apex
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + histone H1
-
Arabidopsis thaliana ADP + phosphorylated histone H1
-
?
ATP + histone H1
-
Arabidopsis thaliana Col-0 ADP + phosphorylated histone H1
-
?

Synonyms

Synonyms Comment Organism
CDKA;1
-
Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP
-
Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction inhibition of CDK activity at the shoot apex results in premature differentiation of shoot apical meristem cells. Cell-cycle inhibition in the STM domain affects cell division in the meristem and the developing organs Arabidopsis thaliana