Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | full activation of CDK2 requires both binding of cyclin A or cyclin E and phosphorylation of residue T160 in the activation segment (also known as the T-loop) by the CDK-activating kinase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P24941 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + histone H1 | - |
Homo sapiens | ADP + phosphorylated histone H1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CDK2 | - |
Homo sapiens |
cyclin-dependent kinase-2 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens | |
cyclin A | full activation of CDK2 requires both binding of cyclin A or cyclin E and phosphorylation of residue T160 in the activation segment (also known as the T-loop) by the CDK-activating kinase | Homo sapiens | |
cyclin E | full activation of CDK2 requires both binding of cyclin A or cyclin E and phosphorylation of residue T160 in the activation segment (also known as the T-loop) by the CDK-activating kinase | Homo sapiens |