Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dynein light chain 1 | interacts with cdk2 and enhances Cdk2 kinase activity in vivo, dynein light chain 1 accelerates the G1-S transition by enhancing the activity of Cdk2 | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | interactions among Cdk2, dynein light chain 1, and cip-interacting zinc finger protein 1 play a regulatory role in cell cycle progression of cancer cells presumably by influencing the levels of nuclear p21WAF1 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Ishikawa cell | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
ZR-75-1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + histone 1 | - |
Homo sapiens | ADP + phosphorylated histone 1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CDK2 | - |
Homo sapiens |
cyclin-dependent kinase 2 | - |
Homo sapiens |