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Literature summary for 2.7.11.22 extracted from

  • Corellou, F.; Camasses, A.; Ligat, L.; Peaucellier, G.; Bouget, F.Y.
    Atypical regulation of a green lineage-specific B-type cyclin-dependent kinase (2005), Plant Physiol., 138, 1627-1636.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.22

Cloned(Commentary)

Cloned (Comment) Organism
complementation of the deficient Saccharomyces cerevisiae cdc28-4 mutant strain by expression of CDKB Ostreococcus tauri

Inhibitors

Inhibitors Comment Organism Structure
Olomoucine
-
 Ostreococcus tauri

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information subcellular localization of CDKA and CDKB Ostreococcus tauri
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Ostreococcus tauri

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
 x * 37000, CDKB, SDS-PAGE, 34000-35000, putative two isoforms of CDKA, SDS-PAGE Ostreococcus tauri

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Ostreococcus tauri CDKB and CDKA are regulated through phosphorylation and cyclins A and B during the cll cycle, regulation overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Ostreococcus tauri
-
 marine unicellular green algae strain isolated from the Thau lagoon, cyclin-dependent kinases CDKB and CDKA, as well as cyclin A and cyclin B are single copy genes, probably two isoforms of CDKA exist
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein CdkB is deactivated by phosphorylation at a Tyr residue through Wee1, reactivating dephosphorylation is performed by Cdc25 Ostreococcus tauri

Purification (Commentary)

Purification (Comment) Organism
CDKA and CDKB by affinity chromatography Ostreococcus tauri

Source Tissue

Source Tissue Comment Organism Textmining
additional information CDKA and CDKB expression and activity analysis during cell cycle Ostreococcus tauri
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + histone H1 substrate of CDKB Ostreococcus tauri ADP + phosphorylated histone H1
-
 ?
additional information CDKB and CDKA are regulated through phosphorylation and cyclins A and B during the cll cycle, regulation overview Ostreococcus tauri ?
-
 ?
additional information CDKB ia a B1-type CDK with A-type features Ostreococcus tauri ?
-
 ?

Subunits

Subunits Comment Organism
? x * 37000, CDKB, SDS-PAGE, 34000-35000, putative two isoforms of CDKA, SDS-PAGE Ostreococcus tauri

Synonyms

Synonyms Comment Organism
B-type cyclin-dependent kinase
-
 Ostreococcus tauri
CDKA
-
 Ostreococcus tauri
CDKB
-
 Ostreococcus tauri

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Ostreococcus tauri

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Ostreococcus tauri
cyclin A complexes with CDKA Ostreococcus tauri
cyclin B complexes with CDKA and CDKB Ostreococcus tauri