Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitotic spindle | - |
Homo sapiens | 72686 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Hice1 subunit of Augmin complex | Homo sapiens | via the formation of the Nedd1-Plk1 complex and subsequent Augmin phosphorylation, Plk1 regulates spindle microtubule-based microtubule nucleation to accomplish normal bipolar spindle formation and mitotic progression | ADP + phosphorylated Hice1 subunit of Augmin complex | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Hice1 subunit of Augmin complex | - |
Homo sapiens | ADP + phosphorylated Hice1 subunit of Augmin complex | - |
? | |
ATP + Hice1 subunit of Augmin complex | via the formation of the Nedd1-Plk1 complex and subsequent Augmin phosphorylation, Plk1 regulates spindle microtubule-based microtubule nucleation to accomplish normal bipolar spindle formation and mitotic progression | Homo sapiens | ADP + phosphorylated Hice1 subunit of Augmin complex | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Plk1 | - |
Homo sapiens |
Polo-like kinase 1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | via the formation of the Nedd1-Plk1 complex and subsequent Augmin phosphorylation, Plk1 regulates spindle microtubule-based microtubule nucleation to accomplish normal bipolar spindle formation and mitotic progression | Homo sapiens |