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Literature summary for 2.7.11.21 extracted from

  • Holland, A.J.; Fachinetti, D.; Da Cruz, S.; Zhu, Q.; Vitre, B.; Lince-Faria, M.; Chen, D.; Parish, N.; Verma, I.M.; Bettencourt-Dias, M.; Cleveland, D.W.
    Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis (2012), Mol. Biol. Cell, 23, 1838-1845.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.21

Localization

Localization Comment Organism GeneOntology No. Textmining
centrosome Plk4 enzyme is localized exclusively to the centrosome, with none accumulated in the spindle midbody Mus musculus 5813
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centrosome Plk4 enzyme is localized exclusively to the centrosome, with none accumulated in the spindle midbody Homo sapiens 5813
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Organism

Organism UniProt Comment Textmining
Homo sapiens O00444
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-
Mus musculus Q64702
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryonic fibroblast
-
 Mus musculus
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embryonic fibroblast
-
 Homo sapiens
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Synonyms

Synonyms Comment Organism
polo-like kinase 4
-
 Mus musculus
polo-like kinase 4
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 Homo sapiens

General Information

General Information Comment Organism
malfunction heterozygosity of Plk4 does not lead to polyploidization and centrosome amplification Mus musculus
malfunction heterozygosity of Plk4 does not lead to polyploidization and centrosome amplification Homo sapiens
physiological function polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis Mus musculus
physiological function polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis Homo sapiens