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Literature summary for 2.7.11.21 extracted from

  • Crasta, K.; Lim, H.H.; Giddings, T.H.; Winey, M.; Surana, U.
    Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle (2008), Nat. Cell Biol., 10, 665-675.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.21

Cloned(Commentary)

Cloned (Comment) Organism
a GST-fusion protein is generated Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
N209A Cdc5KD, kinase-dead mutant Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
centrosome
-
 Saccharomyces cerevisiae 5813
-
spindle
-
 Saccharomyces cerevisiae 5819
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + protein Saccharomyces cerevisiae
-
 ADP + phosphoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + casein
-
 Saccharomyces cerevisiae ADP + phosphorylated casein
-
 ?
ATP + Cdh1
-
 Saccharomyces cerevisiae ADP + phosphorylated Cdh1
-
 ?
ATP + histone H1 substrate used in kinase assay Saccharomyces cerevisiae ADP + phosphorylated histone H1
-
 ?
ATP + protein
-
 Saccharomyces cerevisiae ADP + phosphoprotein
-
 ?

Synonyms

Synonyms Comment Organism
Cdc5
-
 Saccharomyces cerevisiae
Polo kinase
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
 kinase assay at room temperature Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 kinase assay Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Saccharomyces cerevisiae