Application | Comment | Organism |
---|---|---|
additional information | Cdc5 is required to establish contractile actin ring assembly and to maintain it. Cdc5 controls the targeting and activation of Rho1 at the division site via Rho1 guanine nucleotide exchange factors Tus1 and Rom2 | Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
additional information | mutants lacking Cdc5, contractile actin ring assembly is impaired | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Rom2 | Saccharomyces cerevisiae | bound by the polo-box domain of Cdc5 | ADP + phosphorylated Rom2 | - |
? | |
ATP + Tus1 | Saccharomyces cerevisiae | bound by the polo-box domain of Cdc5 | ADP + phosphorylated Tus1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
strains isogenic to BY4741 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Bem3 | bound by the polo-box domain of Cdc5 | Saccharomyces cerevisiae | ADP + phosphorylated Bem3 | - |
? | |
ATP + Ecm25 | bound by the polo-box domain of Cdc5 | Saccharomyces cerevisiae | ADP + phosphorylated Ecm25 | - |
? | |
ATP + Rom2 | bound by the polo-box domain of Cdc5 | Saccharomyces cerevisiae | ADP + phosphorylated Rom2 | - |
? | |
ATP + Sac7 | bound by the polo-box domain of Cdc5 | Saccharomyces cerevisiae | ADP + phosphorylated Sac7 | - |
? | |
ATP + Tus1 | bound by the polo-box domain of Cdc5 | Saccharomyces cerevisiae | ADP + phosphorylated Tus1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cdc5 | - |
Saccharomyces cerevisiae |
polo-like kinase | - |
Saccharomyces cerevisiae |