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Literature summary for 2.7.11.21 extracted from
- Cell-cycle-dependent regulation of telomere binding proteins: roles of Polo-like kinase (2006), Cell Cycle, 5, 1403-1406.
Application
| Application | Comment | Organism |
|---|---|---|
| additional information | Plx1 is required for M phase specific telomere binding of TRF1, is required for efficient loading of TRF1 to mitotic chromatin | Xenopus sp. |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Xenopus sp. | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| egg | - |
Xenopus sp. | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + TRF1 | is phosphorylated by Plx1 upon transition from interphase to M phase, and is recruited to mitotic telomere chromatin | Xenopus sp. | ADP + phosphorylated TRF1 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Plx1 | - |
Xenopus sp. |
| polo-like kinase | - |
Xenopus sp. |
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Release 2023.1 (January 2023)
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