Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | in fertilized eggs between female and male pronuclei at microtubules | Rattus norvegicus | 5737 | - |
germinal vesicle | accumulation of Plk1 in germinal vesicle stage oocytes | Rattus norvegicus | 42585 | - |
microtubule | enzyme is located at and required for microtubule assembly | Rattus norvegicus | 5874 | - |
additional information | localization changes with embryonal development, e.g. throughout the division plane during cytokinesis, subcellular localization analysis, overview, colchicine inhibits spindle pole localization of the enzyme, taxol treatment leads to localization in the cytoplasm | Rattus norvegicus | - |
- |
spindle | middle region, at anaphase-telophase I and anaphase-telophase II stages | Rattus norvegicus | 5819 | - |
spindle pole | after germinal vesicle breakdown, at metaphase I stage, and in MII spindle pole | Rattus norvegicus | 922 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | the enzyme is involved in regulation of cytokinesis and microtubule polymerization modulation during oocyte meiotic maturation, fertilization and early embryonic mitosis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q62673 | female Wistar rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | early | Rattus norvegicus | - |
additional information | enzyme quantity is stable during meiotic maturation | Rattus norvegicus | - |
oocyte | maturing, after activation | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is involved in regulation of cytokinesis and microtubule polymerization modulation during oocyte meiotic maturation, fertilization and early embryonic mitosis | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Plk1 | - |
Rattus norvegicus |
polo-like kinase-1 | - |
Rattus norvegicus |