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Literature summary for 2.7.11.2 extracted from

  • Li, R.J.; Hu, Z.Y.; Zhang, H.S.; Zhan, G.M.; Wang, H.Z.; Hua, W.
    Cloning and functions analysis of a pyruvate dehydrogenase kinase in Brassica napus (2011), Plant Cell Rep., 30, 1533-1540.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
PDK1, cloned from Brassica cDNA library, DNA and amino acid sequence determination and analysis, BnPDK1 is a multi-copy gene, phylogenetic analysis Brassica napus

Protein Variants

Protein Variants Comment Organism
additional information overexpression of BnPDK1 in transgenic Arabidopsis thaliana lines repress the pyruvate dehydrogenase complex activity, and results in the decrease of seed oil content and leaf photosynthesis Brassica napus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Brassica napus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
42000
-
x * 42000, about, sequence calculation Brassica napus

Organism

Organism UniProt Comment Textmining
Brassica napus Q3LTL2 multi-copy gene BnPDK1
-

Source Tissue

Source Tissue Comment Organism Textmining
flower bud
-
Brassica napus
-
leaf
-
Brassica napus
-
additional information BnPDK1 gene is ubiquitously expressed in almost all the tissues tested, having the highest expression in the stamen and the young silique Brassica napus
-
root
-
Brassica napus
-
seed
-
Brassica napus
-
silique
-
Brassica napus
-
stamen
-
Brassica napus
-
stem
-
Brassica napus
-

Subunits

Subunits Comment Organism
? x * 42000, about, sequence calculation Brassica napus

Synonyms

Synonyms Comment Organism
PDK
-
Brassica napus
pyruvate dehydrogenase kinase
-
Brassica napus

General Information

General Information Comment Organism
metabolism mitochondrial pyruvate dehydrogenase complex, a key multienzyme system catalyzing the irreversible conversion of pyruvate to acetyl-CoA and NADH with CO2 as a byproduct, is regulated through inactivation by pyruvate dehydrogenase kinase phosphorylation and reactivation by phospho-PDH phosphatase dephosphorylation Brassica napus
physiological function pyruvate dehydrogenase kinase is a negative regulator of the mitochondrial pyruvate dehydrogenase complex, which plays a key role in intermediary metabolism Brassica napus