Literature summary for 2.7.11.19 extracted from

Chrisman, T.D.; Sobo, G.E.; Exton, J.H.
The Mg2+ requirements of nonactivated and activated rat liver phosphorylase kinase. Inhibition of the activated form by free Mg2+ (1984), FEBS Lett., 167, 295-300.

Search for more literature for 2.7.11.19

Inhibitors

Inhibitors	Comment	Organism	Structure
ATP	free ATP, reversible	Rattus norvegicus
Mg2+	free Mg2+, only activated enzyme, reversible	Rattus norvegicus
Mn2+	free Mn2+	Rattus norvegicus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	-	Rattus norvegicus
Mg2+	requirement	Rattus norvegicus
Mg2+	10 mM	Rattus norvegicus
Mg2+	free Mg2+ inhibits activated enzyme	Rattus norvegicus
Mg2+	free Mg2+ stimulates (nonactivated enzyme)	Rattus norvegicus
Mg2+	major role of Mg2+: cosubstrate in Mg2+-ATP complex	Rattus norvegicus
Mg2+	required for activity phosphorylation by (cAMP-dependent protein kinase)	Rattus norvegicus
phosphate	requirement, phosphate containing enzyme	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + phosphorylase b	cosubstrate: Mg-ATP complex	Rattus norvegicus	ADP + phosphorylase a	-	?

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
30	-	assay at	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)