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Literature summary for 2.7.11.19 extracted from
- Active and inactive protein kinases: structural basis for regulation (1996), Cell, 85, 149-158.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | activation segment structure | Mammalia |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| crystallization of PhK in active conformation | Mammalia |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Mammalia |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + phosphorylase b | Mammalia | - |
ADP + phosphorylase a | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mammalia | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| 2 ATP + phosphorylase b = 2 ADP + phosphorylase a | catalytic aspartate residue | Mammalia |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + phosphorylase b | - |
Mammalia | ADP + phosphorylase a | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | the enzyme has an open, active conformation and a closed, inactive conformation | Mammalia |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PhK | - |
Mammalia |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Mammalia | |
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